The McMaster Multi-Regional Hospital Coronavirus Registry (COREG): Extending a Rapid Research Platform to Inform the Clinical Management of COVID‑19 ‘long haulers’

Beauchamp, Marla K | $497,800

Ontario McMaster University 2021 CIHR Operating Grant

In March of 2020, we launched the McMaster Multi-Regional Hospital Coronavirus Registry (COREG ), a unique COVID‑19 platform that is collecting detailed data on laboratory confirmed COVID‑19 hospital patients, in collaboration with the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC). This platform has collected detailed data on COVID‑19 positive patients (n=2000+) across 7 cohorting hospitals in Kitchener-Waterloo, Hamilton, and Niagara. The COREG platform has also recruited over 130 patients who survived hospitalisation for COVID‑19 to participate in a longer-term study on functional recovery from COVID-19. The COREG functional recovery study is collecting detailed information on symptoms, functioning and health outcomes at 3-,6-, and 9-months after hospital discharge for patients who had serious COVID‑19 illness. Funding for the COREG platform, originally supported by CIHR, expires in June 2021. In light of our preliminary findings suggesting that as many as 70% of our study participants report that COVID‑19 continues to impact their everyday life, we propose to continue our study for another year while expanding its scope. We will continue recruiting patients, add a 12-month follow-up visit, and collect additional information on hospital readmission, vaccination status, as well as study the impact of the new variants of COVID‑19 on short- and long-term patient outcomes. This information is critical for understanding how best to support patients with COVID‑19 in their recovery process in the months and years to come.

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